Résumé :
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The application of microfluidics to biotechnology is an exciting new area that has already begun to revolutionize how researchers study and manipulate macromolecules like DNA, proteins and cells in vitro and within living organisms. Now in a newly revised and greatly expanded second edition, the Artech House bestseller, Microfluidics for Biotechnology brings you to the cutting edge of this burgeoning field with three brand-new chapters and a wealth of additional material throughout the book. Among the numerous updates, the second edition includes discussion on: Nondimensional numbers in microfluidics; Capillarity and microdrops; Two-phase flows (including digital and droplet microfluidics); Cell manipulation and cellular microfluidic systems; Inertial microfluidics and lab-on-chips cell studies; Flow focusing devices for the encapsulation of living cells. Presenting an enlightening balance of numerical approaches, theory, and experimental examples, this book provides a detailed look at the mechanical behavior of the different types of micro/nano particles and macromolecules that are used in biotechnology. Professionals gain a solid understanding of microfluidics theory and the mechanics of microflows and microdrops. The book examines the diffusion of species and nanoparticles, including continuous flow and ballistic random walk. This unique volume describes the transport and dispersion of biochemical species and particles. Engineers and researchers learn how to model biochemical reactions, including DNA hybridization and enzymatic reactions. Moreover, the book helps readers master the theory, applications, and modeling of magnetic beads behavior and provides an overview of self-assembly and magnetic composite. Other key topics include the electric manipulation of micro/nanoparticles and macromolecules and the experimental aspects of biological macromolecule manipulation.
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